目录号:B27704
生物活性: Cholesterol 5beta,6beta-epoxide is an oxidative metabolite of cholesterol formed by free-radical and non-radical oxidation of cholesterol at the 5,6 double bond. [1] [2] Induces lactate dehydrogenase (LDH) release and apoptosis in macrophage-differentiated U937 cells. [3] 5β,6β-epoxycholestanol has been found in human fatty streaks and advanced atherosclerotic lesions, but not in normal aortic tissue. [4] References: [1]. Pulfer, MK, and Murphy, RC Formation of bioactive oxygen sterols during ozonolysis of cholesterol present in lung surfactants. Journal of Biochemistry 279(25), 26331-26338 (2004). [2]. Aringer, L. and Eneroth, P. In vitro formation and metabolism of cholesterol and β-sitosterol 5,6-epoxides. J. Lipid Research. 15(4), 389-398 (1974).[3]. Lordan, S., O'Brien, NM, and Mackrill, JJ Calcium in 7β-hydroxycholesterol and cholesterol-5β,6β-epoxide-induced apoptosis. J. Biochemistry. Moore. poison. 23(5), 324-332 (2009).[4]. Garcia-Cruset, S., Carpenter, KL, Guardiola, F. et al. Oxysterol profiles of normal human arteries, fatty streaks, and advanced lesions. free radicals. reservoir. 35(1), 31-41 (2001).
CAS: 4025-59-6
中文名称:5Β,6Β-环氧胆甾醇
目录号:B27240
生物活性: 5β-Cholanic acid 3,7-dione methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 7753-72-2
中文名称:5β-氯酸3,7-二酮甲酯
目录号:B27700
生物活性: 5β-Cholestane is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 481-20-9
中文名称:假胆甾烷
目录号:B27143
生物活性: Gitoxigenin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 545-26-6
中文名称:芰毒配质
目录号:B27821
生物活性: Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies.
CAS: 148892-91-5
