Cholesterol 5beta,6beta-epoxide  (货号:B27704)

说明书
Cholesterol 5beta,6beta-epoxide
规格价格
50 mg 询价
100 mg 询价
250 mg 询价

货号：B27704

生物活性 Cholesterol 5beta,6beta-epoxide is an oxidative metabolite of cholesterol formed by free-radical and non-radical oxidation of cholesterol at the 5,6 double bond. [1] [2] Induces lactate dehydrogenase (LDH) release and apoptosis in macrophage-differentiated U937 cells. [3] 5β,6β-epoxycholestanol has been found in human fatty streaks and advanced atherosclerotic lesions, but not in normal aortic tissue. [4] References: [1]. Pulfer, MK, and Murphy, RC Formation of bioactive oxygen sterols during ozonolysis of cholesterol present in lung surfactants. Journal of Biochemistry 279(25), 26331-26338 (2004). [2]. Aringer, L. and Eneroth, P. In vitro formation and metabolism of cholesterol and β-sitosterol 5,6-epoxides. J. Lipid Research. 15(4), 389-398 (1974).[3]. Lordan, S., O'Brien, NM, and Mackrill, JJ Calcium in 7β-hydroxycholesterol and cholesterol-5β,6β-epoxide-induced apoptosis. J. Biochemistry. Moore. poison. 23(5), 324-332 (2009).[4]. Garcia-Cruset, S., Carpenter, KL, Guardiola, F. et al. Oxysterol profiles of normal human arteries, fatty streaks, and advanced lesions. free radicals. reservoir. 35(1), 31-41 (2001).
CAS 4025-59-6
中文名称 5Β,6Β-环氧胆甾醇
分子量 402.65
体外研究
体内研究
形式
运输条件 Room temperature in continental US; may vary elsewhere.
保存条件 Please store the product under the recommended conditions in the Certificate of Analysis.
溶解性

相关产品

查找相关产品 >>

产品信息

纯度
说明书

文献引用

暂无数据

客户评价

未选文件 允许的格式：jpg，png 每张图片最大1M，支持多选

Cholesterol 5beta,6beta-epoxide 有 0 条评价