uPA Receptor/U-PAR (YD16933) Rabbit mAb (Cat.#:AYD12908)
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Cat.#
AYD12908
Target / gene
PLAUR
Host
Rabbit
Clonality
Monoclonal
Reactivity
Human
Application
ICC/IF, FC, IP
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Cat.#：AYD12908
| Size | Price | |
|---|---|---|
| 50ul | RMB: 680Sale1280 | Add to cart |
| 100ul | RMB: 1219Sale2300 | Add to cart |
Sales Terms | Request COA | Stock and shipping are confirmed by support
Information
Application guide
Related products
Immunogen
Target data
Resources
FAQs
| Reactivity | Human |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Application | ICC/IFFCIP |
| Dilution | |
| Predicted MW | 37kDa |
| Observed MW | |
| Format | Liquid |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| Conjugate | Unconjugated |
| Positive | DU145,HT-1080,A-549,HeLa,Mouse lung,Rat thymus |
| Subcellular | Cell membrane, Cell projection, invadopodium membrane, Secreted |
| Purification | 亲和纯化 |
Applications and conditions
Where to start
These starting conditions come from the recommended dilution, validation images, and general assay practice. Titrate for your sample and detection system.
ICC/IF
Conditions for ICC/IF
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | DU145,HT-1080,A-549,HeLa,Mouse lung,Rat thymus |
| Key conditions | Optimize fixation, permeabilization, and blocking, and include a secondary-only control |
| Expected result | Expected fluorescence localization: Cell membrane, Cell projection, invadopodium membrane, Secreted |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
FC
Conditions for FC
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | DU145,HT-1080,A-549,HeLa,Mouse lung,Rat thymus |
| Key conditions | For intracellular targets, optimize fixation and permeabilization, and include an isotype control |
| Expected result | Expect the positive population to shift relative to the negative or isotype control |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
IP
Conditions for IP
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | DU145,HT-1080,A-549,HeLa,Mouse lung,Rat thymus |
| Key conditions | Start at the recommended dilution and titrate for your sample and assay |
| Expected result | Expected signal or band near 37kDa |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
Related products
More associated products >>
Immunogen
| Immunogen | Please contact Support |
|---|---|
| Sequence | Request sequence |
Target data
| Background | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
|---|---|
| Gene ID | 5329 |
| Gene name | PLAUR |
| Swiss | Q03405 |
| Synonym | uPA Receptor/U-PAR (YD16933),uPA Receptor/U-PAR (YD16933) Rabbit mAb,PLAUR,Monocyte activation antigen Mo3,MO3,UPAR |
Resources
Validation data
Contact technical support for validation images and application examples.
References
No papers are linked yet. Contact technical support for application examples.
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Support can help confirm the application, sample, dilution, controls, and assay conditions.
Support center
Need help with the application?
Send the catalog number, application, sample type, and assay. Support can confirm dilution, controls, and COA or lot documents.
FAQs
Listed applications: ICC/IF, FC, IP. Use the validation images and recommended dilution as a starting point.
Send the catalog number and lot through the inquiry form. Support will help with the lot documents.
Use the recommended conditions as a starting concentration. Sample, fixation, and detection system may need a titration.