ddGTP (Cat.#:AYB26974)
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Biological activity
Information
Biological activity
| Bioactivity | ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddGTP acts as an inhibitor or a substrate for DNA polymerase α. |
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| CAS | 68726-28-3 |
| Mol.Wt. | 491.18 |
| In vitro | ddGTP inhibits the formation of both negative and positive DNA strands. ddGTP inhibits DNA polymerase α activity in the presence of Mn[2+] at low concentrations ([2]. ddGTP competitively inhibits the incorporation of [3H]dGTP into the DNA. The accuracy of these methods have not been independently confirmed. They are for reference only. |
| Transportation | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Information
| Intro | ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) 是一类双脱氧核糖核苷酸 (ddNTPs)，可作为 DNA 聚合酶链延长抑制剂用于 DNA 测序。ddGTP 是 DNA 聚合酶 α 的抑制剂或也是其反应底物。 |
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| Synonym | 2′,3′-Dideoxyguanosine 5′-triphosphate |