Urokinase (peptidolytic) (Cat.#:AYB26871)
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Biological activity
Information
Biological activity
| Bioactivity | Urokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research. |
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| CAS | 9039-53-6 |
| In vitro | Urokinase peptidolytic(uPA) can increase the expression of uPAR protein and mRNA levels in non-small cell lung cancer (NSCLC). The accuracy of these methods have not been independently confirmed. They are for reference only. |
| Format | Solid |
| Transportation | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Information
| Intro | Urokinase peptidolytic (Urokinase-type plasminogen activator) 是一种丝氨酸蛋白酶，是丝氨酸蛋白酶纤溶酶的一种非活性形式(酶原)。纤溶酶的激活可触发蛋白水解级联反应，进而参与血栓溶解或细胞外基质降解，涉及血管疾病和癌症相关研究。 |
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| Synonym | Urokinase-type plasminogen activator; Uronase; Win 22005; Win-Kinase |