TGF beta Receptor II (YD33771) Rabbit mAb (Cat.#:AYD13044)
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货号
AYD13044
靶点/基因
TGFBR2
宿主
Rabbit
克隆性
Monoclonal
反应种属
Human
应用
ICC/IF, FC
暂无验证图
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Information
应用指南
Related products
Immunogen
Target data
资料与支持
FAQs
| Reactivity | Human |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| 同种型 | IgG |
| Application | ICC/IFFC |
| Dilution | |
| Predicted MW | 65kDa |
| Observed MW | |
| Format | Liquid |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| Conjugate | Unconjugated |
| Positive | Mouse uterus |
| Subcellular | Cell membrane, Membrane raft, Secreted |
| Purification | 亲和纯化 |
应用与推荐条件
快速判断怎么用
以下条件基于推荐浓度、验证图说明与通用实验要求整理，可作为预实验起点；不同样本和检测体系建议做梯度优化。
ICC/IF
ICC/IF 推荐条件
| 推荐稀释 | 请参考验证图说明或咨询技术支持 |
|---|---|
| 建议样本/阳性对照 | Mouse uterus |
| 关键条件 | 建议优化固定、通透和封闭条件，并设置二抗空白对照 |
| 预期结果 | 预期荧光定位：Cell membrane, Membrane raft, Secreted |
| 对照设置 | 建议设置阳性样本、阴性样本和二抗/同型对照 |
FC
FC 推荐条件
| 推荐稀释 | 请参考验证图说明或咨询技术支持 |
|---|---|
| 建议样本/阳性对照 | Mouse uterus |
| 关键条件 | 如检测胞内靶点，需优化固定/通透条件，并设置同型对照 |
| 预期结果 | 预期阳性群体荧光信号相对阴性/同型对照右移 |
| 对照设置 | 建议设置阳性样本、阴性样本和二抗/同型对照 |
Related products
More associated products >>
Immunogen
| Immunogen | 请咨询 技术支持 |
|---|---|
| Sequence | Email For Sequence |
Target data
| Background | This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. |
|---|---|
| Gene ID | 7048 |
| Gene name | TGFBR2 |
| Swiss | P37173 |
| Synonym | TGF beta Receptor II (YD33771),TGF beta Receptor II (YD33771) Rabbit mAb,TGFBR2,TGF-beta type II receptor,Transforming growth factor-beta receptor type II |
资料与技术支持
验证数据
欢迎联系技术支持获取验证图与应用案例。
FAQs
当前页面标注应用包括 ICC/IF, FC，建议结合页面验证图和推荐稀释比例进行预实验优化。
可通过页面询价/留言入口提交货号和批号，技术支持会协助提供对应批次资料。
页面推荐条件可作为起始浓度，不同样本、固定方式和检测体系可能需要梯度优化。