Survivin (YD12833) Rabbit mAb (Cat.#:AYD12540)
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Cat.#：AYD12540
| Size | Price | |
|---|---|---|
| 50ul | RMB: 680Sale1280 | Add to cart |
| 100ul | RMB: 1219Sale2300 | Add to cart |
Sales Terms | Request COA | Stock and shipping are confirmed by support
Information
Application guide
Related products
Immunogen
Target data
Resources
FAQs
| Reactivity | Human,Mouse,Rat |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Application | IHC-PICC/IFFC |
| Dilution | |
| Predicted MW | 16kDa |
| Observed MW | |
| Format | Liquid |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| Conjugate | Unconjugated |
| Positive | HeLa,293F,Jurkat |
| Subcellular | Cytoplasm, Nucleus, Chromosome, centromere, cytoskeleton, spindle, kinetochore, Midbody |
| Purification | 亲和纯化 |
Applications and conditions
These starting conditions come from the recommended dilution, validation images, and general assay practice. Titrate for your sample and detection system.
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | HeLa,293F,Jurkat |
| Key conditions | For paraffin sections, optimize retrieval buffer pH, retrieval time, and primary incubation |
| Expected result | Expected localization: Cytoplasm, Nucleus, Chromosome, centromere, cytoskeleton, spindle, kinetochore, Midbody |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | HeLa,293F,Jurkat |
| Key conditions | Optimize fixation, permeabilization, and blocking, and include a secondary-only control |
| Expected result | Expected fluorescence localization: Cytoplasm, Nucleus, Chromosome, centromere, cytoskeleton, spindle, kinetochore, Midbody |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | HeLa,293F,Jurkat |
| Key conditions | For intracellular targets, optimize fixation and permeabilization, and include an isotype control |
| Expected result | Expect the positive population to shift relative to the negative or isotype control |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
Related products
More associated products >>
Immunogen
| Immunogen | Please contact Support |
|---|---|
| Sequence | Request sequence |
Target data
| Background | This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
|---|---|
| Gene ID | 332 |
| Gene name | BIRC5 |
| Swiss | O15392 |
| Synonym | Survivin (YD12833),Survivin (YD12833) Rabbit mAb,BIRC5,Apoptosis inhibitor 4,Apoptosis inhibitor survivin,API4,IAP4 |
Resources
Validation data
Contact technical support for validation images and application examples.
References
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