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Nisin Z  (Cat.#:AYB27329)

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Cat.#：AYB27329

CAS：137061-46-2

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  • Biological activity

  • Information

Biological activity

Bioactivity Nisin Z is an antimicrobial and anti-inflammatory peptide. Nisin Z is effective against Gram-positive bacteria and fungi, such as C. albicans.
CAS 137061-46-2
Mol.Wt. 3331.05
In vitro

Nisin Z (10 μg/mL, 24 h) 增加牙龈成纤维细胞的脱离和分化。
Nisin Z (25-75 μg/mL，24 小时) 抑制 C. albicans 粘附于牙龈细胞.
Nisin Z (500 和 1000 μg/mL，24 小时) 抑制 C. albicans 胚芽管形成.
Nisin Z (100 μg/mL，12 小时) 减少 MCF10A 细胞中 LPS 诱导的促炎细胞因子 (即 IL-6、TNF-α、IL-1β) 的产生 .
Nisin Z (10-100 μg/mL, 12 h) 抑制 LPS 诱导的 MCF10A 细胞中 ERK1/2 和 p38 MAPK 信号通路的激活。

The accuracy of these methods have not been independently confirmed. They are for reference only.

Cell Viability Assay

Cell Line:C. albicans
Concentration:100, 500, 1000 μg/mL
Incubation Time:24, 48, and 72 h
Result:Reduced C. albicans growth.

Western Blot Analysis

Cell Line:LPS-induced MCF10A cells
Concentration:10-100 μg/mL
Incubation Time:12 h
Result:Inhibited the phosphorylation of p38 and and ERK1/2.
Transportation Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

Information

Intro Nisin Z 是一种抗菌和抗炎肽。Nisin Z 可有效对抗革兰氏阳性菌和真菌 (fungi)，例如 C. albicans。
AYB27329