N-butyryl-L-Homocysteine thiolactone (Cat.#:AYB27781)
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Biological activity
Information
Biological activity
| Bioactivity | Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. The control of bacterial infection by quenching the quorum sensing system of bacteria is a promising research area. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR protein family, is coordinated by the synthesis of diffusible acyl homoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-homoserine lactone, a small, diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and cellular metabolism . N-butyryl-L-homocysteine thiolactone induces violacein expression in Viola viola mutants that normally fail to produce AHL. |
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| CAS | 202284-85-3 |
| Chinese name | N-丁酰基-L-高半胱氨酸硫代内酯 |
| Mol.Wt. | 187.26 |
| Transportation | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Information
| Intro | 群体感应是细菌用来控制基因表达以响应增加的细胞密度的调节系统。通过淬灭细菌的群体感应系统来控制细菌感染是一个很有前途的研究领域。特定目标基因的表达，例如属于 LuxIR 蛋白家族的转录调节因子，由可扩散的酰基高丝氨酸内酯 (AHL) 分子的合成协调。 N-butyryl-L-Homocysteine thio-lactone 是 N-butyryl-L-homoserine lactone 的类似物，N-butyryl-L-homoserine lactone 是参与群体感应的小的可扩散信号分子，从而控制基因表达和细胞代谢。 N-丁酰基-L-高半胱氨酸硫代内酯诱导通常不能产生 AHL 的紫罗兰色堇突变体中紫罗兰素的表达。 |
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| Synonym | N-[(3S)-2-oxothiolan-3-yl]butanamide,N-丁酰基-L-高半胱氨酸硫代内酯 |