MSH3 (YD13366) Rabbit mAb (Cat.#:AYD15600)
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Cat.#：AYD15600
| Size | Price | |
|---|---|---|
| 50ul | RMB: 680Sale1280 | Add to cart |
| 100ul | RMB: 1219Sale2300 | Add to cart |
Sales Terms | Request COA | Stock and shipping are confirmed by support
Information
Application guide
Related products
Immunogen
Target data
Resources
FAQs
| Reactivity | Human |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Application | IHC-PICC/IFFC |
| Dilution | |
| Predicted MW | 127kDa |
| Observed MW | |
| Format | Liquid |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| Conjugate | Unconjugated |
| Positive | SW620 |
| Subcellular | |
| Purification | 亲和纯化 |
Applications and conditions
These starting conditions come from the recommended dilution, validation images, and general assay practice. Titrate for your sample and detection system.
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | SW620 |
| Key conditions | For paraffin sections, optimize retrieval buffer pH, retrieval time, and primary incubation |
| Expected result | Expected staining follows the target localization |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | SW620 |
| Key conditions | Optimize fixation, permeabilization, and blocking, and include a secondary-only control |
| Expected result | Expected fluorescence follows the target localization |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | SW620 |
| Key conditions | For intracellular targets, optimize fixation and permeabilization, and include an isotype control |
| Expected result | Expect the positive population to shift relative to the negative or isotype control |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
Related products
More associated products >>
Immunogen
| Immunogen | Please contact Support |
|---|---|
| Sequence | Request sequence |
Target data
| Background | The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. |
|---|---|
| Gene ID | 4437 |
| Gene name | MSH3 |
| Swiss | P20585 |
| Synonym | MSH3 (YD13366),MSH3 (YD13366) Rabbit mAb,MSH3,Divergent upstream protein,Mismatch repair protein 1,DUC1,DUG |
Resources
Validation data
Contact technical support for validation images and application examples.
References
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