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MMP1 (YD12640) Rabbit mAb  (Cat.#:AYD15747)

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Host: RabbitClonality: MonoclonalReactivity: HumanIHC-PICC/IFFC
Cat.# AYD15747
Target / gene MMP1
Host Rabbit
Clonality Monoclonal
Reactivity Human
Application IHC-P, ICC/IF, FC

Cat.#:AYD15747

SizePrice
50ul RMB: 680Sale1280 Add to cart
100ul RMB: 1219Sale2300 Add to cart
  • Information

  • Application guide

  • Related products

  • Immunogen

  • Target data

  • Resources

  • FAQs

Reactivity Human
Host Rabbit
Clonality Monoclonal
Isotype IgG
Application IHC-PICC/IFFC
Dilution
Predicted MW 54kDa
Observed MW
Format Liquid
Storage Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3.
Conjugate Unconjugated
Positive SKOV3
Subcellular Secreted, extracellular space, extracellular matrix
Purification 亲和纯化

Applications and conditions

Where to start

These starting conditions come from the recommended dilution, validation images, and general assay practice. Titrate for your sample and detection system.

IHC-P Conditions for IHC-P
Recommended dilution See the validation images or contact technical support
Suggested sample / positive control SKOV3
Key conditions For paraffin sections, optimize retrieval buffer pH, retrieval time, and primary incubation
Expected result Expected localization: Secreted, extracellular space, extracellular matrix
Controls Include a positive sample, a negative sample, and a secondary or isotype control
ICC/IF Conditions for ICC/IF
Recommended dilution See the validation images or contact technical support
Suggested sample / positive control SKOV3
Key conditions Optimize fixation, permeabilization, and blocking, and include a secondary-only control
Expected result Expected fluorescence localization: Secreted, extracellular space, extracellular matrix
Controls Include a positive sample, a negative sample, and a secondary or isotype control
FC Conditions for FC
Recommended dilution See the validation images or contact technical support
Suggested sample / positive control SKOV3
Key conditions For intracellular targets, optimize fixation and permeabilization, and include an isotype control
Expected result Expect the positive population to shift relative to the negative or isotype control
Controls Include a positive sample, a negative sample, and a secondary or isotype control

Related products

More associated products >>

Immunogen

Immunogen Please contact Support
Sequence Request sequence

Target data

Background This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Gene ID 4312
Gene name MMP1
Swiss P03956
Synonym MMP1 (YD12640),MMP1 (YD12640) Rabbit mAb,MMP1,Fibroblast collagenase,Matrix metalloproteinase-1,CLG

Resources

Validation data

1 images

Validation images at the top of the page cover IHC-P / ICC/IF / FC.

References

No papers are linked yet. Contact technical support for application examples.

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Support

Support can help confirm the application, sample, dilution, controls, and assay conditions.

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Need help with the application?

Send the catalog number, application, sample type, and assay. Support can confirm dilution, controls, and COA or lot documents.

FAQs

Listed applications: IHC-P, ICC/IF, FC. Use the validation images and recommended dilution as a starting point.
Send the catalog number and lot through the inquiry form. Support will help with the lot documents.
Use the recommended conditions as a starting concentration. Sample, fixation, and detection system may need a titration.
AYD15747