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Lithium citrate tetrahydrate  (Cat.#:AYB26952)

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Cat.#：AYB26952

CAS：6080-58-6

Chinese name：柠檬酸三锂盐四水合物

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100 mg ￥500.00 AddToCart
10 mM * 1 mL in Water ￥550.00 AddToCart

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  • Biological activity

  • Information

Biological activity

Bioactivity Lithium citrate (Litarex) tetrahydrate is the major active ingredient of Garcinia cambogia. Lithium citrate tetrahydrate competitively inhibits ATP citrate lyase with weight loss benefits. Lithium citrate tetrahydrate effective inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation and anti-tumor effects.
CAS 6080-58-6
Chinese name 柠檬酸三锂盐四水合物
Mol.Wt. 281.98
In vitro

Lithium citrate tetrahydrate shows an HIF inhibitory effect compared with the control group in ARPE19 cells and 661W cells. Lithium citrate tetrahydrate can downregulate Hif1a and the downstream genes in ARPE19 cells and 661W cells. Lithium citrate tetrahydrate suppresses HIF-1α protein expression increased by CoCl2 administration in ARPE19 cells and 661W cells.
In chicken hepatocytes, Lithium citrate tetrahydrate decreases the accumulation of lipid droplets and accelerated energy metabolism. Lithium citrate tetrahydrate protects the cells from ER stress by increasing the antioxidant status and mitochondrial functions.

The accuracy of these methods have not been independently confirmed. They are for reference only.
Format Solid
Transportation Room temperature in continental US; may vary elsewhere.
Storage 4°C, sealed storage, away from moisture
Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (354.64 mM)

*"≥" means soluble, but saturation unknown.

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM3.5464 mL17.7318 mL35.4635 mL
5 mM0.7093 mL3.5464 mL7.0927 mL
10 mM0.3546 mL1.7732 mL3.5464 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： PBS

    Solubility: 50 mg/mL (177.32 mM); Clear solution; Need ultrasonic

*以上所有助溶剂都可在 MCE 网站选购。
Purity ≥98.0%

Information

Intro Lithium citrate (Litarex) tetrahydrate 是藤黄果的主要活性成分。Lithium citrate tetrahydrate 可竞争性抑制柠檬酸裂解酶 (ATP citrate lyase) ，并具有减肥效果。Lithium citrate tetrahydrate 有效抑制结石形成并抑制 HIF，具有抗氧化，抗炎和抗肿瘤作用。
Synonym 柠檬酸三锂盐四水合物; Litarex tetrahydrate
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AYB26952