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Kcnip2 (YD32876) Mouse mAb  (Cat.#:AYD21765)

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Host: RabbitClonality: MonoclonalReactivity: Mouse, RatIHC-P
Cat.# AYD21765
Target / gene Kcnip2
Host Rabbit
Clonality Monoclonal
Reactivity Mouse, Rat
Application IHC-P

Cat.#:AYD21765

SizePrice
50ul RMB: 680Sale1280 Add to cart
100ul RMB: 1219Sale2300 Add to cart
  • Information

  • Application guide

  • Immunogen

  • Target data

  • Resources

  • FAQs

Reactivity Mouse, Rat
Host Rabbit
Clonality Monoclonal
Isotype IgG
Application IHC-P
Dilution
Predicted MW 31kDa/31kDa
Observed MW
Format Liquid
Storage Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3.
Conjugate Unconjugated
Positive Hippocampus
Subcellular Cell membrane
Purification 亲和纯化

Applications and conditions

Where to start

These starting conditions come from the recommended dilution, validation images, and general assay practice. Titrate for your sample and detection system.

IHC-P Conditions for IHC-P
Recommended dilution See the validation images or contact technical support
Suggested sample / positive control Hippocampus
Key conditions For paraffin sections, optimize retrieval buffer pH, retrieval time, and primary incubation
Expected result Expected localization: Cell membrane
Controls Include a positive sample, a negative sample, and a secondary or isotype control

Immunogen

Immunogen Please contact Support
Sequence Request sequence

Target data

Background Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels (PubMed:20943905, PubMed:23713033). Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:20943905, PubMed:23713033). Involved in KCND2 and KCND3 trafficking to the cell surface (By similarity). Essential for the expression of I(To) currents in the heart (PubMed:11747815, PubMed:23713033). Required for normal protein levels of KCND2 in the heart ventricle (PubMed:23713033) Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels (PubMed:10676964, PubMed:16820361). Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:10676964, PubMed:16820361). Involved in KCND2 and KCND3 trafficking to the cell surface (By similarity). Essential for the expression of I(To) currents in the heart (By similarity). Required for normal protein levels of KCND2 in the heart ventricle (By similarity)
Gene ID 80906, 56817
Gene name Kcnip2
Swiss Q9JJ69, Q9JM59
Synonym Kcnip2 (YD32876),Kcnip2 (YD32876) Mouse mAb,Kcnip2,Kv channel-interacting protein 2,Potassium channel-interacting protein 2,Kchip2

Resources

Validation data

Contact technical support for validation images and application examples.

References

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Support

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Send the catalog number, application, sample type, and assay. Support can confirm dilution, controls, and COA or lot documents.

FAQs

Listed applications: IHC-P. Use the validation images and recommended dilution as a starting point.
Send the catalog number and lot through the inquiry form. Support will help with the lot documents.
Use the recommended conditions as a starting concentration. Sample, fixation, and detection system may need a titration.
AYD21765