Kcnip2 (YD32876) Mouse mAb (Cat.#:AYD21765)
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Cat.#:AYD21765
| Size | Price | |
|---|---|---|
| 50ul | RMB: 680Sale1280 | Add to cart |
| 100ul | RMB: 1219Sale2300 | Add to cart |
Sales Terms | Request COA | Stock and shipping are confirmed by support
Information
Application guide
Immunogen
Target data
Resources
FAQs
| Reactivity | Mouse, Rat |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Application | IHC-P |
| Dilution | |
| Predicted MW | 31kDa/31kDa |
| Observed MW | |
| Format | Liquid |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| Conjugate | Unconjugated |
| Positive | Hippocampus |
| Subcellular | Cell membrane |
| Purification | 亲和纯化 |
Applications and conditions
These starting conditions come from the recommended dilution, validation images, and general assay practice. Titrate for your sample and detection system.
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | Hippocampus |
| Key conditions | For paraffin sections, optimize retrieval buffer pH, retrieval time, and primary incubation |
| Expected result | Expected localization: Cell membrane |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
Immunogen
| Immunogen | Please contact Support |
|---|---|
| Sequence | Request sequence |
Target data
| Background | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels (PubMed:20943905, PubMed:23713033). Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:20943905, PubMed:23713033). Involved in KCND2 and KCND3 trafficking to the cell surface (By similarity). Essential for the expression of I(To) currents in the heart (PubMed:11747815, PubMed:23713033). Required for normal protein levels of KCND2 in the heart ventricle (PubMed:23713033) Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels (PubMed:10676964, PubMed:16820361). Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:10676964, PubMed:16820361). Involved in KCND2 and KCND3 trafficking to the cell surface (By similarity). Essential for the expression of I(To) currents in the heart (By similarity). Required for normal protein levels of KCND2 in the heart ventricle (By similarity) |
|---|---|
| Gene ID | 80906, 56817 |
| Gene name | Kcnip2 |
| Swiss | Q9JJ69, Q9JM59 |
| Synonym | Kcnip2 (YD32876),Kcnip2 (YD32876) Mouse mAb,Kcnip2,Kv channel-interacting protein 2,Potassium channel-interacting protein 2,Kchip2 |
Resources
Validation data
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References
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