Integrin beta 4 (YD14995) Rabbit mAb (Cat.#:AYD15170)
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货号
AYD15170
靶点/基因
ITGB4
宿主
Rabbit
克隆性
Monoclonal
反应种属
Human
应用
ICC/IF
Information
应用指南
Related products
Immunogen
Target data
资料与支持
FAQs
| Reactivity | Human |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| 同种型 | IgG |
| Application | ICC/IF |
| Dilution | |
| Predicted MW | 202kDa |
| Observed MW | |
| Format | Liquid |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| Conjugate | Unconjugated |
| Positive | A431,BxPC-3,mouse pancreas |
| Subcellular | Cell membrane, Cell junction, hemidesmosome |
| Purification | 亲和纯化 |
应用与推荐条件
快速判断怎么用
以下条件基于推荐浓度、验证图说明与通用实验要求整理，可作为预实验起点；不同样本和检测体系建议做梯度优化。
ICC/IF
ICC/IF 推荐条件
| 推荐稀释 | 请参考验证图说明或咨询技术支持 |
|---|---|
| 建议样本/阳性对照 | A431,BxPC-3,mouse pancreas |
| 关键条件 | 建议优化固定、通透和封闭条件，并设置二抗空白对照 |
| 预期结果 | 预期荧光定位：Cell membrane, Cell junction, hemidesmosome |
| 对照设置 | 建议设置阳性样本、阴性样本和二抗/同型对照 |
Related products
More associated products >>
Immunogen
| Immunogen | Please contact Support |
|---|---|
| Sequence | Email For Sequence |
Target data
| Background | Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
|---|---|
| Gene ID | 3691 |
| Gene name | ITGB4 |
| Swiss | P16144 |
| Synonym | Integrin beta 4 (YD14995),Integrin beta 4 (YD14995) Rabbit mAb,ITGB4,GP150 |
资料与技术支持
验证数据
1 张验证图
页面顶部轮播可查看应用验证图，覆盖 ICC/IF。
FAQs
当前页面标注应用包括 ICC/IF，建议结合页面验证图和推荐稀释比例进行预实验优化。
可通过页面询价/留言入口提交货号和批号，技术支持会协助提供对应批次资料。
页面推荐条件可作为起始浓度，不同样本、固定方式和检测体系可能需要梯度优化。