Guanylyl Imidodiphosphate trisodium (Cat.#:AYB27821)

Name: Guanylyl Imidodiphosphate trisodium
Brand: 艾博立生物
SKU: AYB27821
Availability: OutOfStock

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CAS：148892-91-5

Bioactivity	Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies.
CAS	148892-91-5
Mol.Wt.	591.16
In vitro	Guanylyl Imidodiphosphate trisodium (GppNHp) (100 μM) induces the secretion of dense granules from permeabilized platelets in response to calcium ion stimulation, and GTP-Ral enhances the calcium sensitivity of permeabilized platelet dense granule secretion which is inhibited by Sec5-RBD. Guanylyl Imidodiphosphate trisodium (GppNHp) (0.017-333 μM) causes a significant reduction in the lag time required to stimulate adenylate cyclase activity. The accuracy of these methods have not been independently confirmed. They are for reference only.
Transportation	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

Intro	Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium 是一种不可水解的 GTP 类似物，ADP-核糖基化因子 (ARF) 激活剂，也是腺苷酸环化酶 (adenylate cyclase) 的有效刺激物。Guanylyl Imidodiphosphate trisodium 可用于蛋白质合成研究。
Synonym	Guanosine 5'-[β,γ-imido]triphosphate trisodium

AYB27821