Diethyl maleate (Cat.#:AYB26801)
A
Biological activity
Information
Biological activity
| Bioactivity | Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells. | ||||||||||||||||
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| CAS | 141-05-9 | ||||||||||||||||
| Mol.Wt. | 172.18 | ||||||||||||||||
| Format | Liquid | ||||||||||||||||
| Transportation | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
| Solubility | In Vitro: DMSO : 100 mg/mL (580.79 mM; Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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| Purity | ≥98.0% |
Information
| Intro | Diethyl maleate 是马来酸的两个羧基与乙醇缩合而成的马来酸酯。Diethyl maleate 是一种硫醇反应性 α,β-不饱和羰基化合物,可消耗暴露细胞中的谷胱甘肽 (GSH)。 |
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| Synonym | Maleic acid diethyl ester |
| Rela_targets | Bioactive Compound Library Plus Human Metabolite Library Cuproptosis Compound Library |
