Collagen XVII (YD11428) Rabbit mAb (Cat.#:AYD15993)
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Cat.#：AYD15993
| Size | Price | |
|---|---|---|
| 50ul | RMB: 680Sale1280 | Add to cart |
| 100ul | RMB: 1219Sale2300 | Add to cart |
Sales Terms | Request COA | Stock and shipping are confirmed by support
Information
Application guide
Related products
Immunogen
Target data
Resources
FAQs
| Reactivity | Human |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Application | IHC-PICC/IF |
| Dilution | |
| Predicted MW | 150kDa |
| Observed MW | |
| Format | Liquid |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| Conjugate | Unconjugated |
| Positive | A-431 |
| Subcellular | Cell junction, hemidesmosome, Membrane, Secreted, extracellular space, extracellular matrix, basement membrane |
| Purification | 亲和纯化 |
Applications and conditions
These starting conditions come from the recommended dilution, validation images, and general assay practice. Titrate for your sample and detection system.
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | A-431 |
| Key conditions | For paraffin sections, optimize retrieval buffer pH, retrieval time, and primary incubation |
| Expected result | Expected localization: Cell junction, hemidesmosome, Membrane, Secreted, extracellular space, extracellular matrix, basement membrane |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
| Recommended dilution | See the validation images or contact technical support |
|---|---|
| Suggested sample / positive control | A-431 |
| Key conditions | Optimize fixation, permeabilization, and blocking, and include a secondary-only control |
| Expected result | Expected fluorescence localization: Cell junction, hemidesmosome, Membrane, Secreted, extracellular space, extracellular matrix, basement membrane |
| Controls | Include a positive sample, a negative sample, and a secondary or isotype control |
Related products
More associated products >>
Immunogen
| Immunogen | Please contact Support |
|---|---|
| Sequence | Request sequence |
Target data
| Background | This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008] |
|---|---|
| Gene ID | 1308 |
| Gene name | COL17A1 |
| Swiss | Q9UMD9 |
| Synonym | Collagen XVII (YD11428),Collagen XVII (YD11428) Rabbit mAb,COL17A1,180 kDa bullous pemphigoid antigen 2,Bullous pemphigoid antigen 2,120 kDa linear IgA dermatosis antigen,Linear IgA disease antigen 1,97 kDa linear IgA bullous dermatosis antigen |
Resources
Validation data
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References
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