Catechol O-methyltransferase (Cat.#:AYB27145)
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Biological activity
Information
Biological activity
| Bioactivity | Catechol O-methyltransferase (COMT) the magnesium-dependent transfer of methyl groups from S-adenosyl methionine to a hydroxyl group on dopamine, converting it to 3-methoxytyramine. Catechol O-methyltransferase has two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Catechol O-methyltransferase is to regulate epinephrine, norepinephrine, and dopamine levels in the brain. |
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| CAS | 9012-25-3 |
| Transportation | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Information
| Intro | Catechol O-methyltransferase (COMT) 依赖于镁将甲基从 S-腺苷甲硫氨酸转移到多巴胺上的羟基，将其转化为 3-甲氧基酪胺。Catechol O-methyltransferase 在组织中有两种形式，可溶性形式 (S-COMT) 和膜结合形式 (MB-COMT)。Catechol O-methyltransferase 用于调节大脑中的肾上腺素、去甲肾上腺素和多巴胺水平。 |
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| Synonym | COMT |