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BAPTA tetrapotassium  (Cat.#:AYB27012)

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Cat.#：AYB27012

CAS：73630-08-7

Chinese name：BAPTA四钾盐

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  • Biological activity

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Biological activity

Bioactivity BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators.
CAS 73630-08-7
Chinese name BAPTA四钾盐
Mol.Wt. 628.79
In vitro

BAPTA (0.3-30 μM; 1 h) can be used for the prevention of [Ca2+]-induced cell damage, but disturbe calcium signalling in isingle differentiated NH15-CA2 neuroblastoma and glioma hybrid cells.
BAPTA (0-10 mM) inhibits phospholipase C (PLC) activity in a dose-dependent manner, and is unrelated to Ca2+.

The accuracy of these methods have not been independently confirmed. They are for reference only.
Transportation Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

Information

Intro BAPTA tetrapotassium 是一种选择性的钙离子螯合剂。BAPTA 作为钙离子指示剂，对镁离子和钙离子有较高的选择性。BAPTA tetrapotassium 被广泛用作细胞内缓冲液，用于研究通过质膜 Ca2+ 透性通道从细胞内存储或内流 Ca2+ 释放的影响。BAPTA tetrapotassium 还可抑制磷脂酶 C (phospholipase C) 的活性，与其钙离子螯合特性无关。
Synonym BAPTA四钾盐
AYB27012