Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a prodrug that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts.
CAS
10190-99-5
Chinese name
马兜铃酸I钠盐
Mol.Wt.
363.25
Transportation
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Information
Intro
Aristolochic acid sodium salt (Sodium aristolate 1) 是一些中草药的成分,是造成肾毒性的原因。它是一种前体药物,通过将硝基还原为胺而激活,从而形成细胞毒性 DNA 加合物。
Synonym
Aristolochic acid I sodium,TR 1736 sodium,Sodium aristolochate,马兜铃酸I钠盐