AMP-PNP lithium hydrate (Cat.#:AYB27256)
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Biological activity
Information
Biological activity
| Bioactivity | AMP-PNP lithium hydrate is a non-hydrolyzable analog of ATP. AMP-PNP can replace ATP for biological research and is not hydrolyzed by intracellular enzymes. In the study of BtuCD-F, a vitamin B12 transporter, it was found that AMP-PNP can block the channel formed by the two BtuCDs of the BtuCD-F complex, thereby preventing the entry of vitamin B12. |
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| Transportation | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Information
| Intro | AMP-PNP lithium hydrate 是一种非水解的 ATP 类似物。AMP-PNP 可代替 ATP 用于生物研究，且不会被细胞内的酶水解。在对一种维生素 B12 转运体 BtuCD-F 的研究中发现，AMP-PNP 可堵塞 BtuCD-F 复合物的两个 BtuCD 形成的通道，从而阻止维生素 B12 进入。 |
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| Synonym | Adenylyl imidodiphosphate lithium hydrate |