2′-O-(2-Methoxyethyl)guanosine (Cat.#:AYB26958)
Biological activity
Information
Biological activity
| Bioactivity | 2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA. | ||||||||||||||||
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| CAS | 473278-54-5 | ||||||||||||||||
| Mol.Wt. | 341.32 | ||||||||||||||||
| Format | Solid | ||||||||||||||||
| Transportation | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
| Storage | 4°C, protect from light | ||||||||||||||||
| Solubility | In Vitro: DMSO : 250 mg/mL (732.45 mM; Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
*以上所有助溶剂都可在 MCE 网站选购。 |
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| Purity | 99.81% |
Information
| Intro | 2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG) 是 2'-O-甲氧基乙基修饰的核苷,可以由 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside 酶促转化 (腺苷脱氨酶) 生成。2′-O-(2-Methoxyethyl)guanosine 不能被胞质核苷激酶有效地磷酸化,也不能被掺入细胞的 DNA 或 RNA 中。 |
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| Synonym | 2'-O-MOE-rG |
| Rela_targets | Natural Product-like Compound Library Bioactive Compound Library Plus Cell Cycle/DNA Damage Compound Library Kinase Inhibitor Library Anti-Aging Compound Library Reprogramming Compound Library Nucleotide Compound Library Anti-Lung Cancer Compound Library Anti-Blood Cancer Compound Library Anti-Cancer Metabolism Compound Library Heterocyclic Compound Library |
