目录号:B28071
生物活性: ddCTP is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP is a nucleoside analog that targets the reverse transcriptase of human immunodeficiency virus (HIV). ddCTP can be used for AIDS research.
CAS: 66004-77-1
目录号:B28072
生物活性: 8,11,14-Eicosatriynoic Acid, as an inhibitor of prostaglandins, leukotriene biosynthesis and arachidonic acid-induced platelet aggregation, blocks human 12-lipoxygenase (12-LO), cyclooxygenation The enzyme (COX) and 5-lipoxygenase (5-LO) IC50 values were 0.46 μM, 14 μM and 25 μM, respectively. In addition, it inhibits the action of slow-reacting substances of allergic reactions with IC50 values of 10 μM [1,2]. Lipoxygenase is widely found in fungi, plants and animals, and its content is very high. 12-LO is involved in many important disease states and may play a role in oxidative glutamate toxicity. COX enzymes play complex roles in human physiology and pathology involving the neuronal, immune, renal, cardiovascular, gastrointestinal and reproductive systems. COX enzymes are blocked by aspirin and various other NSAIDs, making them clinically important [3]. 5-LO is involved in cancer pathology. It is expressed by a variety of cancer cells, including colon, lung, breast, and prostate cancers, and promotes cancer cell growth and neovascularization. In vitro: As of now, in vitro studies of 8,11,14-eicosatriynoic acid are still under development. In vivo: To date, in vivo studies of 8,11,14-eicosatriynoic acid are in the development stage. References: [1]. Goetz, J., Sprecher, H., Cornwell, D. and Panganamala, R . Inhibition of prostaglandin biosynthesis by triynoic acid. . prostaglandins. 1976;12(2):187-192. [2]. Sun, F., McGuire, J., Morton, D., Pike, J., Sprecher, H. and Kunau, W. Inhibition of platelet arachidonic acid 12-lipoxygenase by acetylenic acid compounds effect. prostaglandins. 1981;21(2):333-343. [3]. Fitzpatrick, F. Cyclooxygenase: regulation and function. Current Drug Design. 2004;10(6):577-588.
CAS: 34262-64-1
目录号:B28087
生物活性: Azomethine-H (sodium hydrate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 206752-32-1
中文名称:4-羟基-5-(2-羟基苯亚甲基氨基)-萘-2,7-二磺酸 单钠盐 水合物
目录号:B28108
生物活性: Methyl trans-6-Octadecenoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 14620-36-1
中文名称:反岩芹酸甲酯
目录号:B28113
生物活性: Tetraethylammonium Perchlorate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 2567-83-1
中文名称:过氯酸四乙基铵
目录号:B28120
生物活性: D-Galacto-D-mannan from Ceratonia siliqua is a plant cell wall polysaccharide.
CAS: 11078-30-1
中文名称:D-半乳-D-甘露聚糖
目录号:B28139
生物活性: Myristyl laurate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 22412-97-1
中文名称:月桂酸十四烷醇酯
目录号:B28151
生物活性: Tetraethylammonium tetrafluoroborate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 429-06-1
中文名称:四氟硼酸四乙胺
目录号:B28164
生物活性: D-Galactose-6-O-sulfate sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 125455-62-1
中文名称:D-GALACTOSE 6-SULFAT 钠盐
目录号:B28168
生物活性: 6-O-Stearoyl-L-ascorbic Acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 10605-09-1
中文名称:抗坏血酸硬脂酸酯
