目录号:B28366
生物活性: 14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery.
CAS: 186492-53-5
目录号:B26680
生物活性: Gelucire 44/14 is a potential and safe absorption enhancer for improving the absorption of poorly absorbable drugs including insulin and calcitonin by pulmonary delivery.
CAS: 121548-04-7
中文名称:月桂酸聚乙二醇甘油酯
目录号:B28072
生物活性: 8,11,14-Eicosatriynoic Acid, as an inhibitor of prostaglandins, leukotriene biosynthesis and arachidonic acid-induced platelet aggregation, blocks human 12-lipoxygenase (12-LO), cyclooxygenation The enzyme (COX) and 5-lipoxygenase (5-LO) IC50 values were 0.46 μM, 14 μM and 25 μM, respectively. In addition, it inhibits the action of slow-reacting substances of allergic reactions with IC50 values of 10 μM [1,2]. Lipoxygenase is widely found in fungi, plants and animals, and its content is very high. 12-LO is involved in many important disease states and may play a role in oxidative glutamate toxicity. COX enzymes play complex roles in human physiology and pathology involving the neuronal, immune, renal, cardiovascular, gastrointestinal and reproductive systems. COX enzymes are blocked by aspirin and various other NSAIDs, making them clinically important [3]. 5-LO is involved in cancer pathology. It is expressed by a variety of cancer cells, including colon, lung, breast, and prostate cancers, and promotes cancer cell growth and neovascularization. In vitro: As of now, in vitro studies of 8,11,14-eicosatriynoic acid are still under development. In vivo: To date, in vivo studies of 8,11,14-eicosatriynoic acid are in the development stage. References: [1]. Goetz, J., Sprecher, H., Cornwell, D. and Panganamala, R . Inhibition of prostaglandin biosynthesis by triynoic acid. . prostaglandins. 1976;12(2):187-192. [2]. Sun, F., McGuire, J., Morton, D., Pike, J., Sprecher, H. and Kunau, W. Inhibition of platelet arachidonic acid 12-lipoxygenase by acetylenic acid compounds effect. prostaglandins. 1981;21(2):333-343. [3]. Fitzpatrick, F. Cyclooxygenase: regulation and function. Current Drug Design. 2004;10(6):577-588.
CAS: 34262-64-1
目录号:B28038
生物活性: omega-3 Arachidonic Acid ethyl ester is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.
CAS: 123940-93-2
中文名称:(8Z,11Z,14Z,17Z)-ICOSA-8,11,14,17-四烯酸乙酯
目录号:B26936
生物活性: 3-(N,N-Dimethylmyristylammonio)propanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 14933-09-6
中文名称:3-[二甲基(十四烷基)铵]丙烷-1-磺酸盐
目录号:B26992
生物活性: Subtilisin, or rubinase, is a bacterial serine protease. Subtilisin can be used as a detergent additive with thermal stability, pH tolerance, and calcium dependent stability.
CAS: 9014-01-1
目录号:B28305
生物活性: Lesquerolic acid methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 4102-96-9
目录号:B27143
生物活性: Gitoxigenin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 545-26-6
中文名称:芰毒配质
目录号:B27044
生物活性: Quizalofop-ethyl is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 76578-14-8
中文名称:2-[4-(6-氯-2-喹恶啉氧基)-苯氧基]丙酸乙酯
目录号:B27102
生物活性: Meso-?tetraphenylporphyrin?-?pt(ii) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 14187-14-5
中文名称:5,1,15,2-四苯基卟啉铂
