目录号:B27416
生物活性: Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial therapy for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C18-HSL, one of four lipophilic long acyl side chain AHLs produced by the LuxI AHL synthase homolog SinI, is involved in quorum-sensing signaling in strains of Rhizobium meliloti (a nitrogen-fixing bacterial symbiont of the legume M. sativa) . C18-HSL and other hydrophobic AHLs tend to localize in the relatively lipophilic environment of bacterial cells and cannot diffuse freely across the cell membrane. Long-chain N-acyl homoserine lactones can be exported from cells by efflux pumps, or can be transported between communicating cells by extracellular outer membrane vesicles.
CAS: 479050-96-9
中文名称:十八酰基 -L-高丝氨酸内酯
目录号:B27626
生物活性: 3-(Dimethyl(octadecyl)ammonio)propane-1-sulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 13177-41-8
中文名称:十八烷基二甲基(3-磺丙基)氢氧化铵内盐
目录号:B26850
生物活性: Dimethyldioctadecylammonium (bromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 3700-67-2
中文名称:双十八烷基二甲基溴化铵
目录号:B27541
生物活性: Stearyl acetate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 822-23-1
中文名称:乙酸十八酯
目录号:B27570
生物活性: Monoelaidin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 2716-53-2
中文名称:9-十八烯酸(E)-2,3-二羟基丙酯
目录号:B26890
生物活性: Oleic anhydride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 24909-72-6
中文名称:顺式-9-十八碳烯酸酐
目录号:B27019
生物活性: Oleyl Acetate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 693-80-1
中文名称:(Z)-乙酸-9-十八烯基-1-醇酯
目录号:B27111
生物活性: DL-1,3-dihydroxy-2-amino-octadecane is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 13552-09-5
中文名称:2-氨基十八烷-1,3-二醇
目录号:B27147
生物活性: Oleyl oleate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 3687-45-4
中文名称:(Z)-9-十八烯酸-(Z)-9-十八烯酯
目录号:B27199
生物活性: 1-O-Octadecyl-2-O-methyl-rac-glycerol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 84337-43-9
中文名称:1-O-十八烷基-2-O-甲基-rac-甘油
