目录号:B28148
生物活性: Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial therapy for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.
CAS: 216596-71-3
中文名称:N-十一烷酰基-L-高丝氨酸内酯
目录号:B28195
生物活性: Vinyl10-Undecenoate(stabilizedwithMEHQ) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 5299-57-0
中文名称:10-十一碳烯酸乙烯酯
目录号:B28384
生物活性: trans-2-Undecenal is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 53448-07-0
中文名称:TRANS-十一烷-2-烯醛
目录号:B27454
生物活性: Methyl 10-Methylundecanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 5129-56-6
中文名称:10-甲基-十一烷酸及时