目录号:B28148
生物活性: Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial therapy for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.
CAS: 216596-71-3
中文名称:N-十一烷酰基-L-高丝氨酸内酯
目录号:B27416
生物活性: Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial therapy for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C18-HSL, one of four lipophilic long acyl side chain AHLs produced by the LuxI AHL synthase homolog SinI, is involved in quorum-sensing signaling in strains of Rhizobium meliloti (a nitrogen-fixing bacterial symbiont of the legume M. sativa) . C18-HSL and other hydrophobic AHLs tend to localize in the relatively lipophilic environment of bacterial cells and cannot diffuse freely across the cell membrane. Long-chain N-acyl homoserine lactones can be exported from cells by efflux pumps, or can be transported between communicating cells by extracellular outer membrane vesicles.
CAS: 479050-96-9
中文名称:十八酰基 -L-高丝氨酸内酯
目录号:B27131
生物活性: N-Palmitoyl phosphatidylethanolamine (Tripelargonin) is endogenous lipid anorectic hormone, significantly reduces food intake in a dose-dependent manner
CAS: 108321-22-8
目录号:B27813
生物活性: Pyridoxylidene-L-glutamic Acid Dipotassium Salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 13934-03-7
中文名称:吡哆醛-L-谷氨酸二钾盐[药物研究配体]
目录号:B26873
生物活性: Geranyl Acetone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 689-67-8
中文名称:10-二甲基-5
目录号:B28062
生物活性: Endo-1,4-β-xylanase (Xylanase) is an arabinoxylan (AX) degrading enzyme and a glycoside hydrolase, is often used in biochemical studies. Endo-1,4-β-xylanase cleaves the β-xylosidic bond between two d-xylopyranosyl residues linked in β-(1,4).
CAS: 9025-57-4
目录号:B27111
生物活性: DL-1,3-dihydroxy-2-amino-octadecane is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 13552-09-5
中文名称:2-氨基十八烷-1,3-二醇
目录号:B26762
生物活性: 3-Methyl-2-oxovaleric acid (sodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 3715-31-9
中文名称:(+/-)-3-甲基-2-氧戊酸钠
目录号:B27173
生物活性: 2-Amino-2-methyl-1,3-propanediol is a solid-solid phase change materials (PCMs). Amino-2-methyl-1,3-propanediol can be used to make surfactants, vulcanization accelerators and as a biological buffer.
CAS: 115-69-5
目录号:B27293
生物活性: 3-Hydroxy-2-(5-hydroxypentyl)chromen-4-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CAS: 267400-83-9
中文名称:3-羟基-2-(5-羟基戊基)苯并吡喃-4-酮
