p-Aminophenylmercuric acetate (货号:AYB26822)
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生物活性
产品信息
生物活性
| 生物活性 | p-Aminophenylmercuric acetate is an organomercurial activator of matrix metalloproteinases (MMP). P-Aminophenylmercuric acetate participates in the activation and inhibition of MMP-8 by attacking protein sulfhydryl or inducing cysteine switching reaction. p-Aminophenylmercuric acetate promotes the shedding of betacellulin precursor (pro-BTC). p-Aminophenylmercuric acetate influences the binding of agonists and antagonists to the opiate receptor. |
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| CAS | 6283-24-5 |
| 分子量 | 351.75 |
| 体外研究 | p-Aminophenylmercuric acetate (APMA) (0-30 µM；20 min) 减少了大鼠脑匀浆中二氢吗啡结合位点的数量，增加了激动剂对结合钠抑制作用的敏感性。 The accuracy of these methods have not been independently confirmed. They are for reference only. |
| 形式 | Solid |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
产品信息
| Intro | p-Aminophenylmercuric acetate 是一种有机汞基质金属蛋白酶 (MMP) 激活剂。p-Aminophenylmercuric acetate 通过攻击蛋白质巯基或诱导半胱氨酸转换反应，参与 MMP-8 的激活和抑制。p-Aminophenylmercuric acetate 促进了 β 纤维素素前体 (pro-BTC) 脱落。p-Aminophenylmercuric acetate 影响阿片类受体与其激动剂和拮抗剂的结合。 |
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