TCTN1 Rabbit pAb  (货号:B13928)

说明书

货号:B13928

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human,Mouse
宿主 Rabbit
克隆性 Polyclonal
预测反应 IF: Chlamydomonas reinhardtii
应用 WBIF/ICC
推荐浓度 WB: 1:500 - 1:2000
IF/ICC: 1:50 - 1:200
理论分子量 28kDa/52kDa/58kDa/61kDa/63kDa/64kDa
实测分子量 63kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 293T,NCI-H460,Mouse kidney
细胞定位 Cytoplasm,Secreted,cilium basal body,cytoskeleton
纯化 Affinity purification

相关产品

查找相关产品 >>

抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants.
基因ID 79600
基因名 TCTN1
Swiss Q2MV58
别名 TCTN1;JBTS13;TECT1
功能 Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity).

实验步骤

实验步骤

文献引用

暂无数据

客户评价

未选文件 允许的格式:jpg,png 每张图片最大1M,支持多选
5星

TCTN1 Rabbit pAb 有 0 条评价