SORL1 (YD34694) Rabbit mAb (货号:AYD16741)
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抗原信息
靶点信息
| 反应 | Human, Mouse |
|---|---|
| 宿主 | Rabbit |
| 克隆性 | Monoclonal |
| 应用 | ICC/IF |
| 推荐浓度 | |
| 理论分子量 | 248kDa |
| 实测分子量 | |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| 偶联物 | Unconjugated |
| 阳性对照 | SH-SY5Y |
| 细胞定位 | Golgi apparatus membrane, Golgi apparatus, trans-Golgi network membrane, Endosome membrane, Early endosome membrane, Recycling endosome membrane, Endoplasmic reticulum membrane, Endosome, multivesicular body membrane, Cell membrane, Cytoplasmic vesicle, secretory vesicle membrane, Secreted |
| 纯化 |
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| 抗原信息 | 请咨询 技术支持 |
|---|---|
| 序列 | Email For Sequence |
靶点信息
| 研究背景 | This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease. |
|---|---|
| 基因 ID | 6653 |
| 基因名 | SORL1 |
| Swiss | Q92673 |
| 别名 | SORL1 (YD34694) |