SLC7A5 (YD19914) Rabbit mAb (货号:AYD16660)
A
小A
销售顾问
请使用微信扫一扫
添加顾问进行咨询
暂无验证图
欢迎提交实验图片，或联系 技术支持 获取更多信息。
产品信息
相关产品
抗原信息
靶点信息
| 反应 | Human |
|---|---|
| 宿主 | Rabbit |
| 克隆性 | Monoclonal |
| 应用 | IHC-P |
| 推荐浓度 | |
| 理论分子量 | 55kDa |
| 实测分子量 | |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| 偶联物 | Unconjugated |
| 阳性对照 | Mouse testis |
| 细胞定位 | Apical cell membrane, Cell membrane, Lysosome membrane |
| 纯化 |
相关产品
查找相关产品 >>
抗原信息
| 抗原信息 | 请咨询 技术支持 |
|---|---|
| 序列 | Email For Sequence |
靶点信息
| 研究背景 | The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. Functions as an amino acid exchanger. May play a role in the transport of L-DOPA across the blood-brain barrier (By similarity. May act as the major transporter of tyrosine in fibroblasts (Probable. May mediate blood-to-retina L-leucine transport across the inner blood-retinal barrier (By similarity. Can mediate the transport of thyroid hormones triiodothyronine (T3 and thyroxine (T4 across the cell membrane. When associated with LAPTM4B, the heterodimer formed by SLC3A2 and SLC7A5 is recruited to lysosomes to promote leucine uptake into these organelles, and thereby mediates mTORC1 activation. Involved in the uptake of toxic methylmercury (MeHg when administered as the L-cysteine or D,L-homocysteine complexes. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO across the membrane. |
|---|---|
| 基因 ID | 8140 |
| 基因名 | SLC7A5 |
| Swiss | Q01650 |
| 别名 | SLC7A5 (YD19914) |