RNF220 Rabbit pAb  (货号:B18173)

说明书

货号:B18173

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human,Mouse,Rat
宿主 Rabbit
克隆性 Polyclonal
应用 WB
推荐浓度 WB: 1:500 - 1:2000
理论分子量 39kDa/62kDa
实测分子量 75kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 HeLa,Mouse spleen,Mouse thymus,Mouse brain,Rat testis
细胞定位 Cytoplasm
纯化 Affinity purification

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抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling.
基因ID 55182
基因名 RNF220
Swiss Q5VTB9
别名 RNF220;C1orf164
组织表达 Ubiquitously expressed. Abundant in brain and spinal cord, particularly in the cerebellum and cerebral cortex. In fetal tissues expressed in the cerebellum, spinal cord and cortex.
功能 E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).

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