PIP5K1B Rabbit pAb  (货号:B25330)

说明书

货号:B25330

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human,Mouse,Rat
宿主 Rabbit
克隆性 Polyclonal
应用 WBIF/ICC
推荐浓度 WB: 1:500 - 1:2000
IF/ICC: 1:50 - 1:200
理论分子量 56kDa/61kDa/62kDa
实测分子量 71kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 Mouse heart,Mouse lung
细胞定位 Endomembrane system
纯化 Affinity purification

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抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns(4P/PI4P to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5P2/PIP2, a lipid second messenger that regulates several cellular processes such as signal transduction, vesicle trafficking, actin cytoskeleton dynamics, cell adhesion, and cell motility (By similarity. PtdIns(4,5P2 can directly act as a second messenger or can be utilized as a precursor to generate other second messengers: inositol 1,4,5-trisphosphate (IP3, diacylglycerol (DAG or phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5P3/PIP3 (By similarity. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of phospholipase PLD2. Together with PIP5K1A, is required, after stimulation by G-protein coupled receptors, for the synthesis of IP3 that will induce stable platelet adhesion (By similarity.
基因ID 8395
基因名 PIP5K1B
Swiss O14986
别名 PIP5K1B;MSS4;STM7
组织表达 Detected in heart, pancreas, brain, kidney, skeletal muscle and lung.
功能 Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion (By similarity).
研究领域

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