NOXO1 Rabbit pAb  (货号:B14217)

说明书

货号:B14217

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Mouse
宿主 Rabbit
克隆性 Polyclonal
预测反应 WB: Mus musculus
应用 WB
推荐浓度 WB: 1:500 - 1:2000
理论分子量 40kDa/41kDa
实测分子量 41kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 Mouse small intestine,Mouse stomach
细胞定位 Cell membrane,Cytoplasmic side,Peripheral membrane protein
纯化 Affinity purification

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抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 This gene encodes an NADPH oxidase (NOX) organizer, which positively regulates NOX1 and NOX3. The protein contains a PX domain and two SH3 domains. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
基因ID 124056
基因名 NOXO1
Swiss Q8NFA2
别名 NOXO1;P41NOX;P41NOXA;P41NOXB;P41NOXC;SH3PXD5;SNX28
组织表达 Expressed in testis, small and large intestines, liver, kidney and pancreas. Isoform 3 is mainly expressed in colon. Isoform 1 is preferentially expressed in testis.
功能 Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity.

实验步骤

实验步骤

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