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L-Ascorbic acid 2-phosphate magnesium hydrate  (货号:AYB27597)

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货号:AYB27597

CAS:1713265-25-8

规格价格
50 mg 询价
100 mg 询价
250 mg 询价

生物活性

生物活性 L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation.
CAS 1713265-25-8
体外研究

L-Ascorbic acid 2-phosphate (0.1-1.5 mM; 2 to 3 weeks with medium exchange every 2 to 3 days) magnesium hydrate significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc) achieves only weak growth stimulation. A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect . L-Ascorbic acid 2-phosphate (50 µM-250 µM) magnesium hydrate is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 µM AsA2-P and 10 nM dexamethasone (Dex), and 250 µM AsA2-P and 5 nM Dex.

The accuracy of these methods have not been independently confirmed. They are for reference only.

Cell Proliferation Assay

Cell Line:Human corneal endothelial cells (HCECs)
Concentration:0.1 mM; 0.3 mM; 1.5 mM
Incubation Time:2 to 3 weeks with medium exchange every 2 to 3 days
Result:Stimulated HCEC cells growth.
运输条件 Room temperature in continental US; may vary elsewhere.
保存条件 Please store the product under the recommended conditions in the Certificate of Analysis.

产品信息

Intro L-ascorbic acid 2-phosphate magnesium hydrate 是一种长效的维生素 C 衍生物 (vitamin C derivative),可以刺激胶原蛋白的表达和形成。L-ascorbic acid 2-phosphate magnesium hydrate 可以作为培养基补充人脂肪干细胞 (hASCs) 的成骨分化。L-ascorbic acid 2-phosphate magnesium hydrate 增加成骨细胞分化过程中 hASC 中的碱性磷酸酶 (ALP) 活性和 runx2A 的表达。
别名 2-Phospho-L-ascorbic acid magnesium hydrate
AYB27597