HSD17B1 Rabbit pAb  (货号:B10653)

说明书

货号:B10653

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human,Mouse,Rat
宿主 Rabbit
克隆性 Polyclonal
预测反应 WB: Mus musculus , Rattus norvegicus
应用 WBIHCIF/ICC
推荐浓度 WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF/ICC: 1:50 - 1:200
理论分子量 34kDa
实测分子量 35kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 U-87MG,Rat ovary
细胞定位 Cytoplasm
纯化 Affinity purification

相关产品

查找相关产品 >>

抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 This gene encodes a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. This gene is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Polymorphisms in this gene have been linked to breast and prostate cancer. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
基因ID 3292
基因名 HSD17B1
Swiss P14061
别名 HSD17B1;17-beta-HSD;20-alpha-HSD;E2DH;EDH17B2;EDHB17;HSD17;SDR28C1
功能 Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.

实验步骤

实验步骤

文献引用

暂无数据

客户评价

未选文件 允许的格式:jpg,png 每张图片最大1M,支持多选

HSD17B1 Rabbit pAb 有 0 条评价