EXT1 Rabbit pAb  (货号:B15141)

说明书

货号:B15141

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human,Mouse,Rat
宿主 Rabbit
克隆性 Polyclonal
应用 WBIF/ICC
推荐浓度 WB: 1:500 - 1:2000
IF/ICC: 1:50 - 1:200
理论分子量 86kDa
实测分子量 86kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 K-562,SW480,PC-3,Mouse liver,Mouse lung
细胞定位 Endoplasmic reticulum membrane,Golgi apparatus membrane,Single-pass type II membrane protein
纯化 Affinity purification

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抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses.
基因ID 2131
基因名 EXT1
Swiss Q16394
别名 EXT1;EXT;LGCR;LGS;TRPS2;TTV
组织表达 Ubiquitous.
功能 Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

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实验步骤

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