EPHA3/EPHA4/EPHA5 pAb  (货号:B15389)

说明书

货号:B15389

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human,Mouse,Rat
宿主 Rabbit
克隆性 Polyclonal
应用 IHCIF/ICC
推荐浓度 IHC: 1:50 - 1:200
IF/ICC: 1:50 - 1:200
理论分子量
实测分子量
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照
细胞定位 actin cytoskeleton,cytosol,early endosome,extracellular region,nuclear membrane,nucleoplasm,plasma membrane
纯化 Affinity purification

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抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.
基因ID 2042, 2043, 2044
基因名 EPHA3,EPHA4,EPHA5
Swiss P29320, P54764, P54756
别名

实验步骤

实验步骤

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