EGTA (货号:AYB26672)

Name: EGTA
Brand: 艾博立生物
SKU: AYB26672
Availability: InStock

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说明书复制信息复制引用

货号：AYB26672

CAS：67-42-5

规格	价格
Free Sample (0.1 - 0.2 mg)		询价
5 g		询价
10 g		询价
500 mg	￥500.00	加购物车
1 g	￥850.00	加购物车

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销售条款

生物活性
产品信息

生物活性

EGTA is a specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (K_d) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca²⁺ over Mg²⁺ (Mg²⁺ K_d 1-10 mM). EGTA significantly inhibits the substrate adherence capacity of inflammatory macrophages.

CAS

67-42-5

分子量

380.35

体外研究

EGTA, proposed as endodontic irrigant, decreases substrate adherence capacity of inflammatory macrophages in a time- and dose-dependent manner. The EGTA concentration that causes an IC₅₀ is 202 mM. Chelators react with calcium ions in the hydroxyapatite crystals to produce a metallic chelate. Removal of calcium ions from the dentine makes the dentinal tissue softer, especially the hydroxyapatite-rich peritubular dentin and increases the diameter of exposed dentinal tubules.

The accuracy of these methods have not been independently confirmed. They are for reference only.

形式

Solid

运输条件

Room temperature in continental US; may vary elsewhere.

溶解性

In Vitro:

H₂O : 5 mg/mL (13.15 mM; ultrasonic and warming and adjust pH to 9 with NaOH and heat to 60°C)

DMSO : 1 mg/mL (2.63 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.6292 mL	13.1458 mL	26.2916 mL
5 mM	0.5258 mL	2.6292 mL	5.2583 mL
10 mM	0.2629 mL	1.3146 mL	2.6292 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度

≥98.0%

产品信息

Intro	EGTA 是一种特殊的钙离子螯合剂。EGTA 在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。
Rela_targets	Bioactive Compound Library Plus

AYB26672