EDN3 Rabbit pAb  (货号:B17180)

说明书

货号:B17180

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human
宿主 Rabbit
克隆性 Polyclonal
应用 WB
推荐浓度 WB: 1:500 - 1:2000
理论分子量 23kDa/25kDa
实测分子量 44kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 A-549
细胞定位 Secreted
纯化 Affinity purification

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抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.
基因ID 1908
基因名 EDN3
Swiss P14138
别名 EDN3;ET-3;ET3;HSCR4;PPET3;WS4B
组织表达 Expressed in trophoblasts and placental stem villi vessels, but not in cultured placental smooth muscle cells.
功能 Endothelins are endothelium-derived vasoconstrictor peptides.
研究领域

实验步骤

实验步骤

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