D-α-Tocopherol Succinate (货号:AYB26892)

Name: D-α-Tocopherol Succinate
Brand: 艾博立生物
SKU: AYB26892

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货号：AYB26892

CAS：4345-03-3

规格	价格
Free Sample (0.1 - 0.2 mg)		询价
1 g		询价
5 g		询价
100 mg	￥400.00	加购物车
250 mg	￥600.00	加购物车
500 mg	￥760.00	加购物车

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销售条款

生物活性
产品信息

生物活性

D-α-Tocopherol Succinate (Vitamin E succinate) is an antioxidant tocopherol and a salt form of vitamin E. D-α-Tocopherol Succinate inhibits Cisplatin (HY-17394)-induced cytotoxicity. D-α-Tocopherol Succinate can be used for the research of cancer.

CAS

4345-03-3

分子量

530.78

体外研究

D-α-Tocopherol Succinate (1-20 μM; 24 hours) shows cytotoxicity to HEI-OC1 cells. D-α-Tocopherol Succinate (10 μM; 48 hours) protects HEI-OC1 cells against cisplatin-induced ototoxicity and inhibits caspase-3 activity. D-α-Tocopherol Succinate (0-50 μM; 18 hours) shows cytotoxicity to TC-1 tumor cells.

The accuracy of these methods have not been independently confirmed. They are for reference only.

Cell Cytotoxicity Assay

Cell Line:	HEI-OC1 cell line
Concentration:	1-20 μM
Incubation Time:	24 hours
Result:	Significantly induced cytotoxicity at a concentration of 20 μM and showed a higher cytotoxicity potency compared with 10 μM.

Cell Viability Assay

Cell Line:	HEI-OC1 cell line
Concentration:	10 μM
Incubation Time:	48 hours
Result:	Increased cisplatin-induced cell population. Inhibited cisplatin-induced necrotic, ROS production and late apoptosis. Decreased cleaved PARP and inhibited the expression of caspase-3 which related to cisplatin-induced apoptosis.

Cell Cytotoxicity Assay

Cell Line:	TC-1 tumor cells
Concentration:	0, 25 and 50 μM
Incubation Time:	18 hours
Result:	Dose-dependently showed cytotoxic and induced a higher percentage of necrotic TC-1 cells as opposed to apoptotic cells.

形式

Solid

运输条件

Room temperature in continental US; may vary elsewhere.

溶解性

In Vitro:

DMSO : 250 mg/mL (471.00 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.8840 mL	9.4201 mL	18.8402 mL
5 mM	0.3768 mL	1.8840 mL	3.7680 mL
10 mM	0.1884 mL	0.9420 mL	1.8840 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度

≥98.0%

产品信息

Intro	D-α-Tocopherol Succinate (Vitamin E succinate) 是一种抗氧化生育酚，是维生素 E 的一种盐形式。D-α-Tocopherol Succinat 抑制 Cisplatin (HY-17394) 引起的毒性。D-α-Tocopherol Succinate 可用于癌症的研究。
别名	Vitamin E succinate

AYB26892