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DL-β-Hydroxybutyryl coenzyme A lithium  (货号:AYB27976)

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货号:AYB27976

CAS:103404-51-9

规格价格
50 mg 询价
100 mg 询价
250 mg 询价

生物活性

生物活性 DL-β-Hydroxybutyryl coenzyme A lithium is an intermediate in the fermentation of butyric acid and the metabolism of lysine and tryptophan, and is produced from β-hydroxybutyric acid by short-chain-CoA synthase.
CAS 103404-51-9
分子量 874.45
体外研究

DL-β-Hydroxybutyryl coenzyme A lithium (β-Hydroxybutyryl-CoA) can be produced as an intermediate metabolite via the mitochondrial pathway, where impaired mitochondrial function in cancer cells leads to the accumulation of it. At the same time, DL-β-Hydroxybutyryl coenzyme A lithium can also be produced via the fatty acid β-oxidation, which is accelerated by starvation and fasting, leading to the accumulation of it and thus to diseases caused by certain metabolic adaptations.
DL-β-Hydroxybutyryl coenzyme A lithium (β-Hydroxybutyryl-CoA) can act as a cofactor for lysine β-hydroxybutyrylation (Kbhb), with elevated levels of histone Kbhb in a streptozotocin (STZ)-induced type 1 diabetes mellitus (T1DM) mouse model.

The accuracy of these methods have not been independently confirmed. They are for reference only.

运输条件 Room temperature in continental US; may vary elsewhere.
保存条件 Please store the product under the recommended conditions in the Certificate of Analysis.

产品信息

Intro DL-β-Hydroxybutyryl coenzyme A lithium 是丁酸发酵以及赖氨酸和色氨酸代谢的中间体,由 β-羟基丁酸通过短链-CoA 合成酶生成。
AYB27976