CES2 Rabbit pAb  (货号:B18613)

说明书

货号:B18613

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human,Mouse
宿主 Rabbit
克隆性 Polyclonal
应用 WBIF/ICC
推荐浓度 WB: 1:500 - 1:2000
IF/ICC: 1:50 - 1:200
理论分子量 59kDa/61kDa
实测分子量 67kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 SW620,Mouse liver
细胞定位 Endoplasmic reticulum lumen
纯化 Affinity purification

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抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.
基因ID 8824
基因名 CES2
Swiss O00748
别名 CES2;CE-2;CES2A1;PCE-2;iCE
组织表达 Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.
功能 Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine.
研究领域

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