CENPK Rabbit pAb  (货号:B25339)

说明书

货号:B25339

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human
宿主 Rabbit
克隆性 Polyclonal
应用 WB
推荐浓度 WB: 1:500 - 1:2000
理论分子量 31kDa
实测分子量 37kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 HeLa,SKOV3,293T
细胞定位 Chromosome,Nucleus,centromere,kinetochore
纯化 Affinity purification

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抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008]
基因ID 64105
基因名 CENPK
Swiss Q9BS16
别名 CENPK;AF5alpha;CENP-K;FKSG14;P33;Solt
组织表达 Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung and placenta.
功能 Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore.
研究领域

实验步骤

实验步骤

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