Adrenergic Receptor α-2B Antibody (货号:AYP5053)
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产品信息
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抗原信息
靶点信息
| 反应 | Human |
|---|---|
| 宿主 | Rabbit |
| 克隆性 | Polyclonal |
| 应用 | IFELISA |
| 推荐浓度 | IF: 1:50 - 1:200 |
| 理论分子量 | 49kDa |
| 实测分子量 | |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| 偶联物 | Unconjugated |
| 阳性对照 | U-87MG,Mouse skeletal muscle,Mouse kidney,Rat liver,Rat kidney |
| 细胞定位 | Cell membrane,Multi-pass membrane protein |
| 纯化 | Affinity purification |
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抗原信息
| 抗原信息 | Synthesized peptide derived from Human Adrenergic Receptor α-2B. |
|---|---|
| 序列 |
查看序列MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSI |
靶点信息
| 研究背景 | This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. |
|---|---|
| 基因 ID | 151 |
| 基因名 | ADRA2B |
| Swiss | P18089 |
| 别名 | ADRA2B;ADRA2L1;ADRA2RL1;ADRARL1;ALPHA2BAR;FAME2;alpha-2BAR |
| 功能 | Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol. |
| 研究领域 |