ATP6V1C1 Rabbit pAb  (货号:B21299)

说明书

货号:B21299

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human,Mouse
宿主 Rabbit
克隆性 Polyclonal
应用 WB
推荐浓度 WB: 1:500 - 1:2000
理论分子量 43kDa
实测分子量 43kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 U-251MG,293T,Mouse kidney
细胞定位 cytosol,extracellular exosome,extrinsic component of synaptic vesicle membrane,plasma membrane
纯化 Affinity purification

相关产品

查找相关产品 >>

抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.
基因ID 528
基因名 ATP6V1C1
Swiss P21283
别名 ATP6V1C1;ATP6C;ATP6D;VATC;Vma5
组织表达 Ubiquitous.
功能 Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

实验步骤

实验步骤

文献引用

暂无数据

客户评价

未选文件 允许的格式:jpg,png 每张图片最大1M,支持多选
5星

ATP6V1C1 Rabbit pAb 有 0 条评价