AGTRAP Rabbit pAb  (货号:B19803)

说明书

货号:B19803

规格价格
50ul ¥1080.00 加购物车
100ul ¥2050.00 加购物车
反应 Human,Mouse,Rat
宿主 Rabbit
克隆性 Polyclonal
应用 WBIF/ICC
推荐浓度 WB: 1:500 - 1:2000
IF/ICC: 1:50 - 1:200
理论分子量 11kDa/16kDa/17kDa
实测分子量 20kDa
形式 Liquid
保存条件 Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
偶联物 Unconjugated
阳性对照 293T,HT-29,U-87MG,BxPC-3,Mouse kidney,Mouse testis,Mouse heart,Rat kidney,Rat heart
细胞定位 Cytoplasmic vesicle membrane,Endoplasmic reticulum membrane,Golgi apparatus membrane,Multi-pass membrane protein
纯化 Affinity purification

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抗原信息

抗原信息 Recombinant fusion protein.
序列 Email For Sequence

靶点信息

研究背景 This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
基因ID 57085
基因名 AGTRAP
Swiss Q6RW13
别名 AGTRAP;ATRAP
组织表达 Ubiquitous but more abundant in kidney, heart, pancreas and thyroid.
功能 Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
研究领域

实验步骤

实验步骤

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