ABCB11/BSEP (YD20810) Rabbit mAb (货号:AYD12767)
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产品信息
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抗原信息
靶点信息
| 反应 | Human |
|---|---|
| 宿主 | Rabbit |
| 克隆性 | Monoclonal |
| 应用 | IHC-PICC/IFFC |
| 推荐浓度 | |
| 理论分子量 | 146kDa |
| 实测分子量 | |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.75% BSA,50% glycerol,pH7.3. |
| 偶联物 | Unconjugated |
| 阳性对照 | Rat liver |
| 细胞定位 | Apical cell membrane, Recycling endosome membrane, Endosome, Cell membrane |
| 纯化 |
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抗原信息
| 抗原信息 | 请咨询 技术支持 |
|---|---|
| 序列 | Email For Sequence |
靶点信息
| 研究背景 | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. |
|---|---|
| 基因 ID | 8647 |
| 基因名 | ABCB11 |
| Swiss | O95342 |
| 别名 | ABCB11/BSEP (YD20810) |